THE ZEBRAFISH PROGRANULIN GENE FAMILY AND ANTISENSE TRANSCRIPTS

Abstract Background Progranulin is an epithelial tissue growth factor (also known as proepithelin, acrogranin and PC-cell-derived growth factor) that has been implicated in development, wound healing and in the progression of many cancers.The single mammalian progranulin gene encodes a glycoprotein precursor consisting of seven and one half tandeml

We report a case of progressive vitiligo with rosette sign under dermatoscope.A 58-year-old man complained of white patches on the dorsal hands, scrotum and groin for 3 months.Dermatological examination revealed round or irregularly shaped hypopigmented spots or porcelain white read more patches with sharp or undefined boundaries on the dorsal hand